Endocrine Abstracts

Introduction: Turner’s syndrome (TS) affects 1/2500 female births and it is characterized by growth retardation, dysmorphic syndrome and gonadal dysgenesis. Our objective was to describe the clinical, therapeutic and evolutive features of Tunisian patients with TS.Patients and Methods: It was a retrospective study including 23 patients with TS diagnosed between 1993 and 2019.We noted clinical, therapeutic and evolutive data for each patient.<p ...

Introduction: Insulin resistance (IR) is the main pathogenic factor in polycystic ovary syndrome (PCOS) and its complications. Ceylon cinnamon (CC) is an herb with an insulin-sensitizing effect reported in diabetic patients.The aim of our study was to assess the efficiency of CC on the parameters of the IR in patients with (PCOS).Methods: We conducted a prospective interventional study, we included 13 patients with PCOS diagnosed according to the Rotterd...

Resistant hypertension (RH) is defined as blood pressure above a goal despite adherence to at least three optimally dosed antihypertensive medications of different classes, one of which is a diuretic.Objectives: We investigated the prevalence of true resistant hypertension in our Department of Endocrinology, and we described the clinico-biological features of theses patients.Methods: We performed a retrospective descriptive study. ...

Younger people with high blood pressure are 28% less likely to be diagnosed than older people. Arterial hypertension warrants further investigations to exclude secondary causes of hypertension in young people (aged <40 years).Objectives: We conducted a retrospective descriptive study to investigate the characteristics hospitalized hypertensive young adults (<40 years) in our department.Results: The sample included 84 patien...

Low-grade gliomas are the most common brain tumor in children, accounting for 30–50% of central nervous system tumors in the pediatric age group. They can occur anywhere within the central nervous system (CNS) including the optic pathway (5%). When optic gliomas involve the hypothalamus, patients will often present endocrinopathy. Signs of such involvement can include growth failure and precocious puberty. In this report, we present the case of 8 years three months girls ...

Hypohidrotic ectodermal dysplasia (HED) is a rare genetic disorder characterized by the faulty development of the ectodermal structure, resulting in most notably anhydrosis/hypohydrosis, hypotrichosis and hypodontia. Affected individuals tend to have sparse scalp and body hair (Hypohidrotic), absent teeth (hypodontia) or small and pointed teeth. HED is associated with distinctive facial features including a proeminent forehead, thick lips, and flattened bridge of the nose. The...

IntroductionPancreatic cancer is one of the cancers of the digestive tract for which the prognosis has not been improved in terms of early diagnosis. Recent diabetes can be indicative of this pathology.ObservationA 56-year-old man with no notable pathological history who has presented for 04 months a deterioration in general condition with weight loss. On clinical examination: BMI: 17 kg/m2. In bio...

IntroductionCerebral tuberculomas are a rare form of tuberculosis due to the hematogenous spread of Mycobacterium Tuberculosis (MT). Pituitary localization is exceptionally uncommon with total reported cases in the literature fewer than a hundred. Symptoms and radiologic features are nonspecific, leading sometimes to misdiagnosis. We report the rare case of a patient diagnosed with a primary pituitary stalk tuberculosis.Observation...

IntroductionThyrotropin-secreting pituitary adenoma is a rare cause of hyperthyroidism which must be differentiated from other etiologies of inappropriate TSH secretion.Observation:We report the case of a 49 years old male patient with no particular pathological history, addressed for thyrotoxicosis (weight loss, irritability, thermophobia, dyspnea and palpitation) with no goiter or ophtalmopathy. Echocardiog...

Introduction Growth hormone (GH ) deficiency is a rare but not exceptional cause of statural delay in children. The results of GH stimulation tests and the exploration of other pituitary axes allow us to conclude on the nature of the deficiency: total or partial and its possible association with other pituitary deficits.MethodsThis is a retrospective descriptive study including 75 patients followed for congen...